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Ble

Bleはブレオマイシン活性を抑えるブレオマイシン耐性遺伝子。

Gene Accession X52869
InterPro Bleomycin resistance protein family

PDB

  • 1BYL - Antibiotic
    Bleomycin Resistance Protein From Streptoalloteichus Hindustanus
  • 1XRK - Antibiotic Inhibitor
    Crystal Structure Of A Mutant Bleomycin Binding Protein From Streptoalloteichus Hindustanus Displaying Increased Thermostability
    リガンド：BLM|SO4

PDB image

PDB image

References

Crystal structure and site-directed mutagenesis of a bleomycin resistance protein and their significance for drug sequestering.
Dumas P, Bergdoll M, Cagnon C, Masson JM
EMBO J13p2483-92(1994 Jun 1)
The 1.5 A crystal structure of a bleomycin resistance determinant from bleomycin-producing Streptomyces verticillus.
Kawano Y, Kumagai T, Muta K, Matoba Y, Davies J, Sugiyama M
J Mol Biol295p915-25(2000 Jan 28)

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