A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.

1. Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme.
   Berg RA, Prockop DJ
   J Biol Chem248p1175-82(1973 Feb 25)
2. Hydroxylation of (X-Pro-Gly)n by protocollagen proline hydroxylase. Effect of chain length, helical conformation and amino acid sequence in the substrate.
   Kivirikko KI, Kishida Y, Sakakibara S, Prockop DJ
   Biochim Biophys Acta271p347-56(1972 Jul 21)
3. New members of the collagen superfamily.
   Mayne R, Brewton RG
   Curr Opin Cell Biol5p883-90(1993 Oct)

• Amino acid
  • Proline