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en:thromboxane [2013/06/09 10:10] (current)
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 +====== Thromboxane ======
 +One of lipid in a group of eicosanoids. It is involved in platelet aggregation.
 +
 +===== Thromboxane A2 =====
 +An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
 +
 +
 +^ Name | Thromboxane A2(((Z)-7-[(1S,​2S,​3R,​5S)-3-[(E,​3S)-3-hydroxyoct-1-enyl]-4,​7-dioxabicyclo[3.1.1]
 +heptan-2-yl]hept-5-enoic acid)) |
 +^      | TXA<​sub>​2</​sub>,​ TXA-2 |
 +^ Molecular Weight | 352.46508 g/mol |
 +^ Molecular Formula | <​chem>​C20H32O5</​chem>​ |
 +^ XLogP | 4.2 |
 +
 +
 +{{pubchem>​large:​5280497}}
 +
 +
 +
 +===== Thromboxane B2 =====
 +A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin).
 +
 +
 +^ Name | Thromboxane B2(((Z)-7-[(2R,​3S,​4S)-4,​6-dihydroxy-2-[(E,​3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hep
 +t-5-enoic acid)) |
 +^      | TXB<​sub>​2</​sub>,​ TXB-2 |
 +^ Molecular Weight | 370.48036 g/mol |
 +^ Molecular Formula | <​chem>​C20H34O6</​chem>​ |
 +^ XLogP | 3.2 |
 +
 +
 +{{pubchem>​large:​5283137}}
 +
 +
 +
 +
 +====== Reference ======
 +
 +{{pubmed>​long:​1059088}}
 +
 +